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Car Rental

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Looking to rent a car for your stay on Sanibel Island?  Car rentals are a great way to explore the areas around Island Inn and enjoy the scenery of Florida with a leisurely drive. Below is a list of car rental agencies that are available for Sanibel Island that are easily accessible from Southwest Florida International Airport, which is the closest airport to the Island Inn, along with the airport’s address and airport code for reference when making your reservation.

Southwest Florida International Airport (RSW)
11000 Terminal Access Rd
Fort Myers, FL United States 33913
239-590-4800

Company Local Number Reservations
Alamo Rent-A-Car 239-768-2424 800-327-9633
Avis 239-768-2121 800-230-4898
Budget 239-768-1500 800-527-0700
Dollar 239-337-9646 800-800-4000
Enterprise 239-561-2227 800-736-8222
Hertz 239-768-3100 800-654-3131
National 239-768-2100 800-227-7368
Payless Car Rental 239-980-1813 800-729-5377
Sixt 239-204-5781 888-749-8227
Thrifty 239-337-9656 800-847-4389
Fox Rent A Car* 888-849-4218 800-225-4369
Easirent Car Rental* 239-666-3090 888-901-5121
* – Rental car company does not have a check in counter at the airport and is off-property.

Visitor Reviews

5 star rating Tranquility I usually travel alone and I felt completely safe at the Island Inn. The inn is clean and well cared for, everything is in tip-top condition! In addition, the employees were all very kind. The free use of the umbrellas and beach chairs are the icing on the cake! Some other resorts on the island charge you $$ to sit under an umbrella.
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98331 6/11/2025
5 star rating A great place to stay! We just left this wonderful inn. The people were so kind and welcoming, the room (actually more of a condo) was beautiful and had everything we needed. The beach in front of the inn was beautiful and had better shells than most places on the island! The balcony, which was screened in, was beautiful, we ate breakfast there every day! There were chairs and umbrellas on the beach. You can’t beat the sunset as well. This was our first time back to Sanibel since the devastating hurricanes. There were plenty of restaurants open and lots of shops are coming back too. We’ll be back!
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bilingualteach 5/02/2025
5 star rating Return to Paradise We have stayed at the Island Inn many times. However, this was our first stay since the hurricanes hit Sanibel. The rooms in Matthews Lodge were just as great as ever. The beach had a great many more shells. The chairs and umbrellas made sitting on the beach very peaceful and enjoyable. The staff was as friendly and welcoming as ever. While so much has changed, we were glad to support the Island Inn and all the other familiar businesses on Sanibel. It is important to show your loyalty to such a wonderful place and the people who live and work there. We will be back again in the near future!
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D4593FJpatriciac 4/28/2025

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