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Car Rental

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Looking to rent a car for your stay on Sanibel Island?  Car rentals are a great way to explore the areas around Island Inn and enjoy the scenery of Florida with a leisurely drive. Below is a list of car rental agencies that are available for Sanibel Island that are easily accessible from Southwest Florida International Airport, which is the closest airport to the Island Inn, along with the airport’s address and airport code for reference when making your reservation.

Southwest Florida International Airport (RSW)
11000 Terminal Access Rd
Fort Myers, FL United States 33913
239-590-4800

Company Local Number Reservations
Alamo Rent-A-Car 239-768-2424 800-327-9633
Avis 239-768-2121 800-230-4898
Budget 239-768-1500 800-527-0700
Dollar 239-337-9646 800-800-4000
Enterprise 239-561-2227 800-736-8222
Hertz 239-768-3100 800-654-3131
National 239-768-2100 800-227-7368
Payless Car Rental 239-980-1813 800-729-5377
Sixt 239-204-5781 888-749-8227
Thrifty 239-337-9656 800-847-4389
Fox Rent A Car* 888-849-4218 800-225-4369
Easirent Car Rental* 239-666-3090 888-901-5121
* – Rental car company does not have a check in counter at the airport and is off-property.

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Visitor Reviews

5 star rating Hurricane survivor does it right. Our first visit to Sanibel and the Island Inn was a great choice. The room was perfect - very clean and well-appointed with a full kitchen, comfortable furniture and a huge screened in deck patio. Convenient parking under the building, and centrally located on a great section of beach. The staff was great in our limited contacts, and made the check in and out process very easy. Staff also sets up and takes down beach umbrellas for guest use a great touch. There was lots of construction (they continue to rebuild after Hurricane Ian) but the noise was very low and almost unnoticeable from the beach. Looking forward to what they accomplish in the coming year.
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Steve 4/01/2026
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